Endocrine Abstracts

Background: Acute intermittent porphyria (AIP) is characterized by attacks of abdominal pain and neuropsychiatric symptoms. This disease is more frequently and more severely affecting women. Hem deficiency in the liver of AIP patients stimulates an increase in ALA-synthase which triggers an escalating metabolic chain reaction, leading to an increase in the porphyrin content. Treatment of AIP is carbohydrate-rich diet and by treating the attacks with intravenous infusions of gl...

Background: Most common tumors in the suprasellar region are adenomas of the pituitary gland, craniopharyngiomas, cystic lesions (Rathke’s cleft cysts). Supraselar meningiomas are rare and slow-growing tumors that usually arise from the tuberculum sellae or the chiasmatic sulcus. These tumors frequently invade the sella turcica because that they are mistaken for a pituitary tumor.Methods: A case seriesResults: We present a two...

A pheochromocytoma is a rare, catecholamine-secreting tumor that may precipitate life-threatening hypertension. The tumor is malignant in 10% of cases. Although pheochromocytoma has classically been associated with von Hippel-Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN 2), and neurofibromatosis type 1 (NF1) there are now 10 genes that have been identified as sites of mutations leading to pheochromocytoma.Method and materials A case re...